Effect of Laryngeal EMG-guided Botulinum Toxin Injection on Spasmodic Dysphonia

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J Korean Soc Laryngol Phoniatr Logop > Volume 8(2); 1997 > Article

Journal of The Korean Society of Laryngology, Phoniatrics and Logopedics 1997;8(2): 204-209.

연측성 발성장애 환자에서 후두근전도를 이용한 보툴리눔독소 주입술의 효과

최홍식, 문형진, 서진원, 김성국, 김광문

연세대학교 의과대학 이비인후과학교실, 음성언어의학연구소

Effect of Laryngeal EMG-guided Botulinum Toxin Injection on Spasmodic Dysphonia

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ABSTRACT

In the treatment of spasmodic dysphonia, laryngeal injection of botulinum toxin has been reported to be successful. The treatment of adductor type spasmodic dysphonia with botulinum toxin type A injection using EMG was conducted in 24 patients and it's effect was compared with results from flexible nasopharyngoscopy guided injection(29 patients) and telelaryngoscopy guided injection(31 patients). Sixty two point five percent(62.5%) of patients using EMG and 75.8% of patients using flexible nasopharyngoscope and 90.0% of patients using telelaryngoscope reported that the patient's symptom was improved. The functional status of the patient's disorder was classified into low grades. The mean pre-injection grade for patients using EMG, flexible nasopharyngoscope and telelaryngoscope was 1.7, 1.6 and 2.1 respectively. And it was lowered to 1.0, 0.7 and 1.1 respectively after the injection.
Results
were similar(p＜0.05). As a self assessment method, patients were asked to rate their voice on a scale of 100. In this study, the mean pre-injection score was 66.3, 44.0 and 40.0 respectively. And it was improved to 74.8, 77.7 and 69.8 respectively after the injection. Among 23 patients who undergone above 3method, 17 patients(73.9%) told that EMG-guided botulinum injection was preferable method in its convenience and effectiveness. In conclusion, EMG guided botulinum toxin injection is an another effective method for the treatment of adductor type spasmodic dysphonia similar to telelaryngoscopy-guided injection and flexible nasopharyngoscopy guided injection.

KEY WORDS： Botulinum toxin;Spasmodic dysphonia;EMG;Flexible nasopharyngoscope;Telelaryngoscope;